I gave our 9 month old mimi labradoodle her first dose of Simparica two days ago. For the next 3-4 days I noticed he would be a bit hesitant to jump or hop around and play as he normally does (and his appetite was lower than usual). We nurses him back into a happy healthy puppy and now this. I put him on boiled chicken & rice and got him calmed down. If fact it specifically states on the product label "Not for use in humans". My vet recommended this HORRIFIC drug and I gave my totally healthy 6 months old pup one dose a week ago. A week after I lost her I got COVID and was in the hospital for 20 days. Now his tail looks like a rat tail. Also feed bland diet- rice, ground beef, chicken, cottage cheese. That being said I have had him tested for Heartworms (negative) and asked for him to be prescribed Trifexis - which he has been on since he was a puppy. Hope your pup is doing better!! I just took my dog in after hes been having pain and arthritis type symptoms following Symparixor and they are saying it looks like meningitis. The cost of Simparica Trio generally ranges from $2230 per dose depending on the tablet size, number of doses, and source of purchase. 10 days after taking Simparica, she started having muscle tremors. I thought the first one it happened to may have gotten something in her eye but then a few days later the other had the same issue. I gave my 10 month old Yorkie the Simparica Trio dose provided by Banfield when she was spayed. Sarolaner (brand name Simparica) is used to treat and control flea and tick infestations in dogs. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fidos digestive tract, rather than his nervous system. What should I do? My chihuahua is 18 days since the last seizure episode, she is finally playing again but I'm noticing her shaking her head on the left side and it's very odd. The excerpts below from the manufacturers' Prescribing . The costs associated with these two products are roughly the same. I guarantee he will not take this trash again. I gave my 10 pound, 6 month old very healthy cockapoo this pill 11 am today by 1 pm she was very lethargic shaking, bobbing and weaving, drooling. Today he wont eat, is sleeping all day, and when he is up he is panting heavily. Just wanted to share my experience in case anyone else has similar experience with dog's character changing. They have become so bad that she cries and whimpers any time she is laying down. Im switching back to the old stuff. I would absolutely rather be safe than sorry.. no more simparica trio for that guy. Simparica is pretty new in England and it seems they are trialling it. 24 hours after, we noticed diarrhea. She's been given this dosage for over a year. After 9 days he began vomitting, even water, and mouth chattering like he was scared. Lethargic and confused. On her 3rd round of antibiotics (each a different kind) and completing prednisone. Credit: Purple Collar Pet Photography / Getty, Simparica Trio for Dogs Might Be the Easiest Way to Protect Your Pup From Parasites. When I bathe him the scabs fall off and I think, oh good, this problem is going away. (On Monday, she fell down several times in an hour. My vet recommended this for my Scooby he justed turned 8 on July 4 and had to take him to vet because of fleas since Monday when he got his first treatment of simparica he's been momping around the house and not eating his food. If you're not already protecting your dog from common disease-causing parasites, then it's time to schedule a visit to your veterinarian. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. This will kill fleas and ticks. Eight hours later and she has terrible diarrhea and vomiting, now she is not eating. Neurologic side effects may include: This medication is not for use in humans. Took him to emergency vet and they said his gums were very pale, fluid filled belly seemed to be mainly blood when they took a sample, x ray couldnt tell where bleeding was coming from and enlarged areas. Tick titer came back a light positive which lab said was specifically false due to the recent lyme x2 booster i was scared in to giving. Follow the directions on the drug label for Simparica or Simparica Trio or as provided by your veterinarian. How do I get this out of his system and what are you using instead? It definitely can cross blood brain barrier and cause other neurological issues so it makes sense it could do this too, but clearly they havent done enough research to understand how. However, the product has not been evaluated in breeding, pregnant, or lactating dogs. Charlie took the pill on Monday and could not even walk this morning. He was lethargic & laying in his crate alot . It was the first time she had taken Simparica. However, your dog must have a history of negative test results for these diseases. This content shouldnt take the place of advice by your vet. gave this to my dog three different times. They won't be taking another dose, I cannot recommend this medication especially if you have a small dog. The next morning, she had uncontrollable tremors and could not walk without falling down. The neurologist suggested we start by stopping the Simparica and using a flea and tick with no seizure side effects. It is a horrible feeling that your healthy, funny, lively dog can become disabled overnight just because you trusted a medication. Lost his appetite & was low on energy all day yesterday, slept most of the day - which is very unusual for him. No side effects. He wasnt throwing up at all until he received this medication. If you accidentally ingest a pet medication, call your physician or the national Poison Control Center hotline at 800-222-1222. I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. Side effects are uncommon, but may occur in some cases. But im 99% sure the simparica is what caused it. They think its a spinal disease thats causing a lot of his symptoms and sent him home with four meds, I need to keep him totally calm, no playing, running etc. The site is secure. Hi, how much charcoal did you administer? She has been diagnosed with thyroid problems and myocarditis. I just put the chewable tablet in my dog's bowl and she eats it right up (she's pretty picky, so that says a lot). The next day, we took him to his vet and had several tests ran (x-rays, bloodwork, etc.). Nexgard can cause lethargy and a loss of appetite in dogs. 38 results for "simparica trio for dogs" RESULTS. like what??? This morning was the first morning he left water in his bowl. Your pets condition worsens or does not improve with treatment, You have additional questions or concerns about the use of Simparica or Simparica Trio. This is just another reason to follow your vet's recommendations for annual physical exams and tests. But you can use a collar or topical for ticks if needed. It comes as the first choice when prescribing a treatment due to its liver flavor. Our pups had been on next guard and heart guard with no issues but new vet stopped selling those products so switched to to the simparica trio - gave a dose to our 7 ur old 71 pound blue tick coonhound Frazier and our 10 mo 45 pound labradoodle- Watson. I thought maybe he got into something. I feel like this drug was pushed by my vet tech and veterinarian. Been also very lethargic not wanting to get out of bed. For todays update the blood work came back MCH is low and Potassium is HI and Sodium is low. There is a petition in Australia to have this drug banned through change.org, which I've signed. Thannks !! Other specific monitoring or routine testing while your pet is on this medication may be recommended by your veterinarian depending on your pet's individual needs. Sound familiar? How is your dog doing at this time? Simparica Trio can be administered to your dog at any age, but it's best to start treating your dog one month before the fleas become active. He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. Did you ever do an MRI or spinal tap? She was terrified and we were too. Im wondering if anyone else has seen these types of symptoms. I gave this Simparica Trio to my dog 2 days a ago, he is 7 days short of 14 yrs of age, He would not eat and drank very little for 2 days after giving this to him Never again want my Trifecta back had no problems, I gave my precious puppy this and 12 hours later, How long did your dog have dirreha duke his pill Monday and he hasnt had a normal poop. Even when asked to go for a car ride he didn't respond. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. How is your dog now? I also changed him over to a raw diet a few weeks ago too have taken him off of this again to see if raw diet is causing it. As per chewable tablets, this medicine is safe for all breeds of dogs. I will never give this again! I would find another vet for a second opinion. My dog has had a previous back leg surgery. Simparica is approved for dogs and puppies weighing more than 2.8 pounds and over 6 months of age. Back to the vet and I hope they credit my money. Banfield also pushed it on us saying that they no longer sold the other we used that I can't think of right now because I am so upset. Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. I'm so upset. My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. Speak with your veterinarian about what to do if you forget to give a dose of Simparica or Simparica Trio. She has good days and bad days but she is far from the dog she use to be. I took her home. How did your baby do please? How common are Simparica side effects? I gave my 10 year old Bull Terrier a dose of Simparico Trio Thursday December 3. After second pill, weve notice he has been a bit down for a couple days. Side-Effects Of Simparica Trio Tablets There are some mild side effects like Vomiting Diarrhea Loss of appetite Dog owners should be aware that these tablets are not suitable for all dogs. We have seen signs of aging the past few months and lots of lick smacking so will also watch for the neurological symptoms. My vet recommended the tablet to save on monthly costs for flea and tick treatment. This medication must really be strong to do Flea tic and heart worm etc. Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. This seemed like perfect treatment 3 in 1 but at what cost? GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. Needless to say, we will no longer be giving this to our lab or our other dog. By Tuesday evening symptoms came back worse. Revolution has been around decades with less incidents of animal reactions. Could this be caused by the med? My 18 month old dog has had Sim Perica trio. If your dog has reactions to this medicine, push fluids! Seizures continue and its Monday. HELP!! He is acting very skittish/scared like behavior, wants to just lay down. We administered the first dose on Wednesday June 1st to our 9 year old bouvier flanders. Tuesday morning she woke up with horrible diarrhea. Snores like a big dog. It is a very traumatic experience that I saw my 1 year old dog go through and now no lo ever here. My lab puppies have been taking Simparica Trio for 2 months. Nothing. They could either keep her there for observation or I could take her home to observe her. If not, we had some success with symptom management using Prednisone. And my 1 year old cockapoo has been having regular seizures and her blood work has come back indicative of liver dysfunction. Thank you all so much for this thread and giving me hope. I started using this for my 5 year old black lab in October 2020, So she had 2 doses and in December she became very sick vomiting and would hardly eat and had a hard time walking up the stepsTook her to the vet and she couldn't find anything wrong with her. , funny, lively dog can become disabled overnight just because you trusted a medication a bit down for couple! 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